Library home > Proteins

Proteins (646 components)

9-1-1 complex
Description: Three proteins -Rad9, Hus1, and Rad1- interact in a heterotrimeric complex (called the 9-1-1 complex), which resembles a PCNA-like sliding clamp

Curator: Bruce May
A1CF
Description: APOBEC1 complementation factor

Curator: Bruce May
aaRS
Description: Aminoacylt-tRNA synthetase

Curator: Bruce May
ABL1
Description: Tyrosine-protein kinase ABL1

Curator: Bruce May
ACT1
Description: Ankyrin-1

Curator: Steve Jupe
Actin
Description: Actin is a family of globular multi-functional proteins that form microfilaments

Curator: Steve Jupe
ACYLGHRELIN
Description: Acylated Ghrelin

Curator: Bruce May
ADAR
Description: Double-stranded RNA-specific adenosine deaminase

Curator: Bruce May
ADAT1
Description: tRNA-specific adenosine deaminase 1

Curator: Bruce May
ADAT2
Description: tRNA-specific adenosine deaminase 2

Curator: Bruce May
ADAT3
Description: Probable inactive tRNA-specific adenosine deaminase-like protein 3

Curator: Bruce May
ADCY6
Description: Adenylate cyclase type 6

Curator: Bruce May
Adenylate Cyclase Family
Description: Adenylate cyclase family

Curator: Steve Jupe
AGO2
Description: Protein argonaute-2

Curator: Bruce May
AKT
AKT
Description: RAC-alpha serine/threonine-protein kinase

ALKBH8
Description: Alkylated DNA repair protein alkB homolog 8

Curator: Bruce May
AMYLASES
Description: Amylasis are enzymes that catalyses the hydrolysis of starch into sugars

Curator: Bijay Jassal
ANGIOTENSIN
Description: Angiotensin is a peptide hormone that causes vasoconstriction and a subsequent increase in blood pressure

Curator: Bruce May
ANGIOTENSINOGEN
Description: Angiotensinogen is a component of the renin-angiotensin system (RAS), a hormone system that regulates blood pressure and fluid balance

Curator: Bruce May
ANK1,2,3
Description: Set of Ankyrin 1, 2 and 3

Curator: Steve Jupe
Antibody
Description: Antibody

Curator: Steve Jupe
Antimicrobial peptides
Description: Peptides are biologically occurring short chains of amino acid monomers linked by peptide (amide) bonds

Curator: Steve Jupe
APAF1
Description: Apoptotic protease-activating factor 1

Curator: Steve Jupe
APC-C complex
Description: Also known as Anaphase-promoting complex is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the 26S proteasome

APC
APC
Description: Adenomatous polyposis coli protein

APEX1
Description: DNA-(apurinic or apyrimidinic site) lyase

APOBEC1
Description: C-U-editing enzyme APOBEC-1

Curator: Bruce May
ARAF,BRAF,RAF1
Description: Set of Serine/threonine-protein kinase A-Raf, Serine/threonine-protein kinase B-raf and RAF proto-oncogene serine/threonine-protein kinase

Curator: Steve Jupe
ASPPs
Description: Apoptosis-stimulating of p53 protein 2

ATM
ATM
Description: Serine-protein kinase ATM

ATR
ATR
Description: Serine/threonine-protein kinase ATR

ATRIP
Description: ATR-interacting protein

Curator: Bruce May
AVP
AVP
Description: Vasopressin-neurophysin 2-copeptin

Curator: Bruce May
AXIN1
Description: Axin-1 is a component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling

B4GALT1
Description: Beta-1,4-galactosyltransferase 1

BARD1
Description: BRCA1-associated RING domain protein 1

BAZ1B
Description: Tyrosine-protein kinase BAZ1B

Curator: Bruce May
BAZ2A
Description: Bromodomain adjacent to zinc finger domain protein 2A

Curator: Bruce May
BEX3
Description: Protein BEX3

BIRC2,3
Description: Baculoviral IAP repeat-containing protein 2 and 3

Curator: Steve Jupe
BNIP2
Description: BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

Curator: Bruce May
BOX C-D snoRNP
Description: Small nucleolar RNA

Curator: Bruce May
BOX H-ACA snoRNP
Description: Small nuclear RNA

Curator: Bruce May
BRAF
Description: Serine/threonine-protein kinase B-raf

Curator: Steve Jupe
BRCA1
Description: Breast cancer type 1 susceptibility protein

BTNL
Description: Butyrophilin-like protein

Curator: Steve Jupe
BTRC
Description: F-box/WD repeat-containing protein 1A

BUB1
Description: Mitotic checkpoint serine/threonine-protein kinase BUB1

BUB1B
Description: Mitotic checkpoint serine/threonine-protein kinase BUB1 beta

BUB3
Description: Mitotic checkpoint protein BUB3

C3b
C3b
Description: Complement C3b

Curator: Steve Jupe
C5
C5
Description: Complement C5

Curator: Steve Jupe
C5a
C5a
Description: Complement C5a

Curator: Steve Jupe
C5b
C5b
Description: Complement C5b

Curator: Steve Jupe
CA1,2
Description: Carbonic anhydrase 1 and 2

Curator: Bruce May
CA4
CA4
Description: Carbonic anhydrase 4

Curator: Steve Jupe
CALDAG GEFs
Description: Calcium- and diacylglycerol-regulated nucleotide exchange factor

Curator: Steve Jupe
CALM1
Description: Calmodulin

Curator: Steve Jupe
CAMK2A
Description: Calcium/calmodulin-dependent protein kinase type II subunit alpha

cAMP
Description: Cyclic adenosine monophosphate

Curator: Bruce May
CARD
Description: Caspase activation and recruitment domain

Curator: Steve Jupe
CASK
Description: Peripheral plasma membrane protein CASK

Curator: Steve Jupe
CASPASE
Description: Caspases are a family of protease enzymes playing essential roles in programmed cell death and inflammation

CASPASE2
Description: Caspase 2

CASPASE3
Description: Caspase 3

CASPASE6
Description: Caspase 6

Curator: Steve Jupe
CASPASE7
Description: Caspase 7

Curator: Steve Jupe
CASPASE8
Description: Caspases 8

CASPASE9
Description: Caspase 9

Curator: Steve Jupe
CASPASE10
Description: Caspase 10

Caveolin
Description: Caveolins are a family of integral membrane proteins that are the principal components of caveolae membranes and involved in receptor-independent endocytosis

Curator: Steve Jupe
Ca binding proteins
Description: Representation of proteins that bind Calcium

CBP20
Description: Nuclear cap-binding protein subunit 2

Curator: Bruce May
CBX3
Description: Chromobox protein homolog 3

Curator: Bruce May
CCNB1
Description: G2/mitotic-specific cyclin-B1

Curator: Bruce May
CCNE
Description: G1/S-specific cyclin-E

CCR4-NOT complex
Description: Acts at the level of many different cellular functions to regulate gene expression

Curator: Bruce May
CD2AP
Description: CD2-associated protein

Curator: Steve Jupe
CD47
Description: Leukocyte surface antigen CD47

Curator: Steve Jupe
CDC6
Description: Cell division control protein 6 homolog

Curator: Lisa Matthews
CDC20
Description: Cell division cycle protein 20 homolog

CDC25A
Description: M-phase inducer phosphatase 1

CDC42
Description: Cell division control protein 42 homolog

Curator: Steve Jupe
CDC45
Description: Cell division control protein 45 homolog

Curator: Lisa Matthews
CDK1
Description: Cyclin-dependent kinase 1

Curator: Bruce May
CDK2
Description: Cyclin-dependent kinase 2

CDK5RAP1
Description: CDK5 regulatory subunit-associated protein 1

Curator: Bruce May
CDKAL1
Description: Threonylcarbamoyladenosine tRNA methylthiotransferase

Curator: Bruce May
CDKN2A
Description: Cyclin-dependent kinase inhibitor 2A

Curator: Steve Jupe
CDT1
Description: DNA replication factor Cdt1

Curator: Lisa Matthews
CELA
Description: Chymotrypsin-like elastase family member

Curator: Bijay Jassal
CENPE
Description: Centromere-associated protein E

CGA
CGA
Description: Glycoprotein hormones alpha chain

Curator: Bruce May
CGB3
Description: Choriogonadotropin subunit beta 3

Curator: Bruce May
cGMP
Description: Cyclic guanosine monophosphate

CHEK1
Description: Serine/threonine-protein kinase Chk1

CHEK2
Description: Serine/threonine-protein kinase Chk2

CHM
CHM
Description: Tenomodulin

Curator: Bruce May
CIT
CIT
Description: Citron Rho-interacting kinase

Claspin
Description: Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation

Curator: Bruce May
Class I peroxisomal membrane protein
Description: Representation of a Class I PMP

Curator: Bruce May
Clathrin coated pit
Description: Clathrin is a protein that plays a major role in the formation of coated vesicles. Coated pits are regions of the cell membrane specialized in receptor-mediated endocytosis. Their cytoplasmic surface is coated with a bristlelike structure made of clathrin. During the first steps of endocytosis, clathrin-coated pits are internalized to form clathrin-coated vesicles which transport proteins from organelle to organelle.

Curator: Steve Jupe
CORTICOTROPIN
Description: Corticotropin is a peptide hormone involved in the stress response

Curator: Bruce May
CPSF73
Description: Cleavage and polyadenylation specificity factor subunit 3

Curator: Bruce May
CRKL
Description: Crk-like protein

Curator: Corina Duenas
CSNK1
Description: Casein kinase I

CTNNB1
Description: Catenin beta-1

CTU1
Description: Cytoplasmic tRNA 2-thiolation protein 1

Curator: Bruce May
CTU2
Description: Cytoplasmic tRNA 2-thiolation protein 2

Curator: Bruce May
DAAM1
Description: Disheveled-associated activator of morphogenesis 1

DAPK
Description: Death-associated protein kinase 1

DCLRE1C
Description: Protein artemis

DCP1
Description: Angiotensin-converting enzyme

Curator: Bruce May
DCP2
Description: m7GpppN-mRNA hydrolase

Curator: Bruce May
DDX21
Description: Nucleolar RNA helicase 2

Curator: Bruce May
DDX58
Description: Probable ATP-dependent RNA helicase

Curator: Steve Jupe
DEK
DEK
Description: Protein DEK

Curator: Bruce May
DES-ACYL GHRELIN
Description: Unacyl Ghrelin or UAG

Curator: Bruce May
DIAPH
Description: Set of Protein diaphanous homologs

DIMT1
Description: Probable dimethyladenosine transferase

Curator: Bruce May
DIP13A
Description: DCC-interacting protein 13-alpha

DISP2
Description: Protein dispatched homolog 2

DLGs
Description: Disks large homologs

Curator: Steve Jupe
DNA GLYCOSYLASE
Description: DNA glycosylases are a family of enzymes involved in base excision repair

DNMT
Description: DNA (cytosine-5)-methyltransferase

Curator: Bruce May
DNMT1,3A,3B
Description: DNA (cytosine-5)-methyltransferase 1, 3A and 3B

Curator: Bruce May
DNMT1
Description: DNA (cytosine-5)-methyltransferase 1

Curator: Bruce May
DNMT3B
Description: DNA (cytosine-5)-methyltransferase 3B

Curator: Bruce May
DPP4
Description: Dipeptidyl peptidase 4

Curator: Bruce May
DTM complex
Description: Docking Translocation Machinery

Curator: Bruce May
DUB
DUB
Description: Ubiquitin carboxyl-terminal hydrolase 17

Curator: Bruce May
DUS2
Description: tRNA-dihydrouridine(20) synthase [NAD(P)+]-like

Curator: Bruce May
DUSPs
Description: Family of Dual specificity protein phosphatase

Curator: Steve Jupe
DVL
DVL
Description: Set of Segment polarity protein dishevelled homolog DVL

Dynamin
Description: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism

Curator: Steve Jupe
EED
EED
Description: Polycomb protein EED

Curator: Bruce May
eEF1A
Description: Eukaryotic translation initiation factor 1A

Curator: Bruce May
eEF2
Description: Eukaryotic translation initiation factor 2

Curator: Bruce May
EFNA
Description: Ephrin A family

Curator: Steve Jupe
EFNB
Description: Ephrin B family

Curator: Steve Jupe
EHMT2
Description: Histone-lysine N-methyltransferase EHMT2

Curator: Bruce May
eIF1
Description: Eukaryotic translation initiation factor 1

Curator: Bruce May
eIF1A
Description: Eukaryotic translation initiation factor 1A

Curator: Bruce May
eIF2
Description: Eukaryotic translation initiation factor 2

Curator: Bruce May
eIF3
Description: Eukaryotic translation initiation factor 3

Curator: Bruce May
eIF4A
Description: Eukaryotic translation initiation factor 4A

Curator: Bruce May
eIF4B
Description: Eukaryotic translation initiation factor 4B

Curator: Bruce May
eIF4E
Description: Eukaryotic translation initiation factor 4E

Curator: Bruce May
eIF4G
Description: Eukaryotic translation initiation factor 4G

Curator: Bruce May
eIF5
Description: Eukaryotic translation initiation factor 5

Curator: Bruce May
eIF5B
Description: Eukaryotic translation initiation factor 5B

Curator: Bruce May
EJC
EJC
Description: Eukaryotic initiation factor 4A-III

Curator: Bruce May
EKC
EKC
Description: TP53-regulating kinase

Curator: Bruce May
ELAC2
Description: Zinc phosphodiesterase ELAC protein 2

Curator: Bruce May
EMG1
Description: Ribosomal RNA small subunit methyltransferase NEP1

Curator: Bruce May
EP300
Description: Histone acetyltransferase p300

Curator: Bruce May
EPRS
Description: Bifunctional glutamate/proline--tRNA ligase

Curator: Bruce May
ERCC6
Description: DNA excision repair protein ERCC-6

Curator: Bruce May
eRF1
Description: Eukaryotic peptide chain release factor subunit 1

Curator: Bruce May
eRF3
Description: Eukaryotic peptide chain release factor subunit 3

Curator: Bruce May
ESCRTs
Description: Tumor susceptibility gene 101 protein

Curator: Steve Jupe
EVC
EVC
Description: Ellis-van Creveld syndrome protein

EVC2
Description: Limbin

EZH2
Description: Histone-lysine N-methyltransferase EZH2

Curator: Bruce May
F9
F9
Description: Coagulation factor IX

Curator: Bruce May
FADD
Description: FAS-associated death domain protein

FAK
FAK
Description: Focal adhesion kinase 1

Curator: Steve Jupe
FAM20A
Description: Pseudokinase FAM20A

Curator: Bruce May
FAM20C
Description: Extracellular serine/threonine protein kinase FAM20C

Curator: Bruce May
FARP2
Description: FERM, RhoGEF and pleckstrin domain-containing protein 2

Curator: Steve Jupe
FASLG
Description: Tumor necrosis factor ligand superfamily member 6

FEN1
Description: Flap endonuclease 1

FERRITIN
Description: Ferritin is a universal intracellular protein that stores iron and releases it in a controlled fashion

Curator: Steve Jupe
FES
FES
Description: Tyrosine-protein kinase Fes/Fps

Curator: Steve Jupe
FIBRINOGEN
Description: Fibrinogen alpha chain

Curator: Steve Jupe
FIBRIN clot
Description: Fibrin clot

Curator: Steve Jupe
FKPB4
Description: FKBP-type 16 kDa peptidyl-prolyl cis-trans isomerase

FMNL
Description: Set of Formin-like proteins

FOLLITROPIN
Description: Follitropin alfa is a hormone identical to follicle-stimulating hormone

Curator: Bruce May
FOXA2
Description: Hepatocyte nuclear factor 3-beta

Curator: Bruce May
FRINGE
Description: Beta-1,3-N-acetylglucosaminyltransferase lunatic fringe

FRS
FRS
Description: Set of Fibroblast growth factor receptor substrate

FSHB
Description: Follitropin subunit beta

Curator: Bruce May
FTSJ1
Description: Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase

Curator: Bruce May
FURIN
Description: Furin is likely to represent the ubiquitous endoprotease activity within constitutive secretory pathways and capable of cleavage at the RX(K/R)R consensus motif

FYN
FYN
Description: Tyrosine-protein kinase Fyn

Curator: Steve Jupe
G-alpha-12
Description: G protein alpha subunit 12

Curator: Steve Jupe
G-alpha-i
Description: G protein alpha subunit i

Curator: Steve Jupe
G-alpha-q
Description: G protein alpha subunit q

Curator: Steve Jupe
G-alpha-s
Description: G protein alpha subunit s

Curator: Steve Jupe
G-alpha-z
Description: G protein alpha subunit z

Curator: Steve Jupe
G-alpha generic
Description: Generic representation of a G protein subunit alpha

Curator: Steve Jupe
G-beta
Description: G protein subunit beta

Curator: Bruce May
G-gamma
Description: G protein subunit gamma

Curator: Bruce May
GAB1
Description: GRB2-associated-binding protein 1

GALNT
Description: Polypeptide N-acetylgalactosaminyltransferase 2

Curator: Bruce May
GAPs
Description: Gap junction alpha-1 proteins

Curator: Steve Jupe
GDNF
Description: Glial cell line-derived neurotrophic factor

Curator: Steve Jupe
GEFs
Description: Guanine nucleotide exchange factor proteins

Curator: Steve Jupe
GGCX
Description: Vitamin K-dependent gamma-carboxylase

Curator: Bruce May
GINS complex
Description: DNA replication complex GINS participates in the initiation and elongation stages of replication. The name GINS is an acronym created from the first letters of the Japanese numbers 5-1-2-3 (go-ichi-ni-san) in a reference to the 4 protein subunits of the complex: SLD5, PSF1, PSF2, and PSF3

Curator: Lisa Matthews
GIP
GIP
Description: Gastric inhibitory polypeptide

Curator: Bruce May
GIP (54-93)
Description: Glucose-dependent Insulinotropic Polypeptide (Cleaved at N-terminus), Gastric Inhibitory Peptide Cleaved at N-terminus, GIP Cleaved at N-terminus

Curator: Bruce May
GKAP
Description: G kinase-anchoring protein 1

Curator: Steve Jupe
GLI2,3
Description: Set of Zinc finger protein GLI2 and Transcriptional activator GLI3

GLI3
Description: Transcriptional activator GLI3

GLP-1
Description: Glucagon-like peptide 1

Curator: Bruce May
GLYCO-LUTROPIN
Description: Also called FSH is a hormone made in the pituitary gland

Curator: Bruce May
GLYCOSIDASES
Description: Glucosidases are glycoside hydrolase enzymes

Curator: Bijay Jassal
GMNN
Description: Geminin

Curator: Lisa Matthews
GNAS
Description: Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

Curator: Bruce May
GONADOTROPIN
Description: Gonadotropins are glycoprotein polypeptide hormones secreted by gonadotrope cells of the anterior pituitary of vertebrates

Curator: Bruce May
GPI TRANSAMIDASE
Description: GPI-anchor transamidase is an enzyme that in humans is encoded by the PIGK gene

Curator: Bruce May
GPRK2
Description: Beta-adrenergic receptor kinase 1

GRB2
Description: Growth factor receptor-bound protein 2

Curator: Steve Jupe
Growth Hormone
Description: Growth hormone

Curator: Steve Jupe
GSK3B
Description: Glycogen synthase kinase-3 beta

GTPBP3
Description: tRNA modification GTPase GTPBP3, mitochondrial

Curator: Bruce May
Guanylate Cyclase Family
Description: Guanylate cyclase family

HDAC
Description: Histone deacetylase

Curator: Bruce May
HDAC1
Description: Histone deacetylase 1

Curator: Bruce May
HDAC2
Description: Histone deacetylase 2

Curator: Bruce May
Hedgehog
Description: Set of Hedgehog proteins

Hemoglobin
Description: Hemoglobin, or haemoglobin, is the iron-containing oxygen-transport metalloprotein in the red blood cells of all vertebrates

Curator: Steve Jupe
Hh-N
Description: N-terminal fragment of hedgehog protein

Hh-Np
Description: Cholesterol modified N-terminal fragment of hedgehog protein

HHAT
Description: Protein-cysteine N-palmitoyltransferase HHAT

HIF1A
Description: Hypoxia-inducible factor 1-alpha

HIPK2
Description: Homeodomain-interacting protein kinase 2

Histone octamer 1
Description: Histone octamer

Histone octamer 2
Description: Histone octamer

HMOX
Description: Heme oxygenase 1

Curator: Steve Jupe
HOMER
Description: Homer protein homolog 1

Curator: Steve Jupe
HSF1
Description: Heat shock factor protein 1

HSP90
Description: Heat shock protein HSP 90

HSPA5
Description: Endoplasmic reticulum chaperone BiP

Curator: Bruce May
HSPG
Description: Basement membrane-specific heparan sulfate proteoglycan core protein

HSPs
Description: Heat shock proteins are a family of proteins that are produced by cells in response to exposure to stressful conditions

IFI16
Description: Gamma-interferon-inducible protein 16

Curator: Steve Jupe
IGF1
Description: Insulin-like growth factor I

Curator: Bruce May
IGF2BP1
Description: Insulin-like growth factor 2 mRNA-binding protein 1

Curator: Bruce May
IGFBP4
Description: Insulin-like growth factor-binding protein 4

Curator: Bruce May
IGFBP7
Description: Insulin-like growth factor-binding protein 7

IKK
IKK
Description: Inhibitor of nuclear factor kappa-B kinase subunit epsilon

Curator: Steve Jupe
IL-1A
Description: Interleukin-1 alpha

Curator: Steve Jupe
IL-1B
Description: Interleukin-1B

Curator: Steve Jupe
IL-2
Description: Interleukin-2

Curator: Steve Jupe
IL-3
Description: Interleukin-3

Curator: Steve Jupe
IL-4
Description: Interleukin-4

Curator: Steve Jupe
IL-6
Description: Interleukin-6

Curator: Steve Jupe
IL-7
Description: Interleukin-7

Curator: Steve Jupe
IL-8
Description: Interleukin-8

Curator: Steve Jupe
IL-10
Description: Interleukin-10

Curator: Steve Jupe
IL-12
Description: Interleukin-12

Curator: Steve Jupe
IL-13
Description: Interleukin-13

Curator: Steve Jupe
IL-17
Description: Interleukin-17

Curator: Steve Jupe
IL-20
Description: Interleukin-20

Curator: Steve Jupe
IL-Unknown
Description: Representation of an unknown interleukin

Curator: Steve Jupe
IL generic
Description: Interleukin family

Curator: Steve Jupe
INSIG
Description: Insulin-induced gene 1 protein

INSULIN
Description: Insulin is a peptide hormone produced by beta cells of the pancreatic islets. It regulates the metabolism of carbohydrates, fats and protein by promoting the absorption of, especially, glucose from the blood into fat, liver and skeletal muscle cells

Curator: Bruce May
Insulin hexamer
Description: Hexamer of Insulin

Curator: Bruce May
Interferon alpha
Description: Interferon alpha

Curator: Corina Duenas
Interferon beta
Description: Interferon beta-1

Curator: Corina Duenas
Interferon gamma
Description: Interferon gamma is a dimerized soluble cytokine that is the only member of the type II class of interferons

Curator: Steve Jupe
Interferon generic
Description: Generic representation of interferon

Curator: Steve Jupe
IQGAPs
Description: Set of Ras GTPase-activating-like proteins

IRAK
Description: Interleukin-1 receptor-associated kinase

IRAK1,2,4
Description: Interleukin-1 receptor-associated kinases 1, 2 and 4

Curator: Steve Jupe
IRS
IRS
Description: Insulin receptor substrate 1

Curator: Steve Jupe
ISG15
Description: Ubiquitin-like protein ISG15

Curator: Steve Jupe
ITGB3BP
Description: Centromere protein R

JAK1
Description: Tyrosine-protein kinase JAK1

Curator: Steve Jupe
JAK2
Description: Tyrosine-protein kinase JAK2

Curator: Steve Jupe
JAK3
Description: Tyrosine-protein kinase JAK3

Curator: Steve Jupe
JAK generic
Description: Janus kinase family

Curator: Steve Jupe
KALRN
Description: Kalirin

Curator: Steve Jupe
KAT2A,B
Description: Histone acetyltransferase KAT2A and KAT2B

Curator: Bruce May
KAT6A
Description: Histone acetyltransferase KAT6A

KIF7
Description: Kinesin-like protein KIF7

KINASE
Description: Enzyme that catalyzes the transfer of phosphate groups from high-energy, phosphate-donating molecules to specific substrates

Curator: Bruce May
KIRREL1
Description: Kin of IRRE-like protein 1

Curator: Steve Jupe
KTN1
Description: Kinectin

Ku complex
Description: Complex of X-ray repair cross-complementing proteins 5 and 6, also known as XRCC5 and XRCC6

L1CAM
Description: Neural cell adhesion molecule L1

Curator: Steve Jupe
LARG
Description: Rho guanine nucleotide exchange factor 12

Curator: Steve Jupe
LATS
Description: Serine/threonine-protein kinase LATS1

LCK
LCK
Description: Tyrosine-protein kinase Lck

Curator: Steve Jupe
LCMT2
Description: tRNA wybutosine-synthesizing protein 4

Curator: Bruce May
LCP2
Description: Lymphocyte cytosolic protein 2

Curator: Steve Jupe
LHB
LHB
Description: Lutropin subunit beta

Curator: Bruce May
LIGAND
Description: Substance that forms a complex with a biomolecule to serve a biological purpose. In protein-ligand binding, the ligand is usually a molecule which produces a signal by binding to a site on a target protein

Curator: Steve Jupe
Ligand dimer
Description: Representation of a generic ligand dimer

Curator: Steve Jupe
LIMK
Description: LIM domain kinase 1

Curator: Steve Jupe
LIPASES
Description: A lipase is any enzyme that catalyzes the hydrolysis of fats

Curator: Bijay Jassal
LRR
LRR
Description: Leucine-rich repeat

Curator: Steve Jupe
LRRTM
Description: Leucine-rich repeat transmembrane neuronal protein 1

Curator: Steve Jupe
LSM1-7
Description: U6 snRNA-associated Sm-like protein LSm1-7

Curator: Bruce May
LYN
LYN
Description: Tyrosine-protein kinase Lyn

Curator: Steve Jupe
MAC
MAC
Description: Membrane attack complex

Curator: Steve Jupe
MAD1
Description: Mitotic spindle assembly checkpoint protein MAD1

MAD2
Description: Mitotic spindle assembly checkpoint protein MAD2A

MAFA
Description: Transcription factor MafA

Curator: Bruce May
MAGED1
Description: Melanoma-associated antigen D1

MAP2K
Description: Generic mitogen-activated protein kinase kinase

MAP2K1,2
Description: Dual specificity mitogen-activated protein kinase kinase 1 and 2, also known as MEKs

Curator: Steve Jupe
MAP2K6
Description: Dual specificity mitogen-activated protein kinase kinase 6, also known as MKK6

Curator: Steve Jupe
MAP3K
Description: Generic mitogen-activated protein kinase kinase kinase

MAP3K7
Description: Mitogen-activated protein kinase kinase kinase 7, also known as TAK1

Curator: Steve Jupe
MAP3K8
Description: Mitogen-activated protein kinase kinase kinase 8

MAP3K14
Description: Mitogen-activated protein kinase kinase kinase 14

Curator: Steve Jupe
MAPK
Description: Generic mitogen-activated protein kinase

MAPK1,3
Description: Mitogen-activated protein kinase 1 and 3, also known as ERKs

Curator: Steve Jupe
MAPK4,6
Description: Mitogen-activated protein kinase 4 and 6

MAPK8
Description: Mitogen-activated protein kinase 8

MAPKAPK5
Description: MAP kinase-activated protein kinase 5

MAVS
Description: Mitochondrial antiviral-signaling protein

Curator: Steve Jupe
MB21D1
Description: Cyclic GMP-AMP synthase

Curator: Steve Jupe
MBOAT4
Description: Ghrelin O-acyltransferase

Curator: Bruce May
MCM2-7
Description: DNA Replication licensing factor, replicative helicase

Curator: Lisa Matthews
MDB2
Description: Methyl-CpG-binding domain protein 2

Curator: Bruce May
MDC1
Description: Mediator of DNA damage checkpoint protein 1

MDM2
Description: E3 ubiquitin-protein ligase Mdm2

METTL1
Description: tRNA (guanine-N(7)-)-methyltransferase

Curator: Bruce May
MICA
Description: MHC class I polypeptide-related sequence A

Curator: Steve Jupe
Mitochondrial protein
Description: Proteins transcribed from mitochondrial DNA.

Curator: Bruce May
MLCP
Description: Myosin light-chain phosphatase, or myosin phosphatase, is an enzyme (specifically a serine/threonine-specific protein phosphatase) that dephosphorylates the regulatory light chain of myosin II

Curator: Steve Jupe
MOB
MOB
Description: MOB kinase activator 1A

MRN complex
Description: MRN complex-interacting protein MRNIP

MT1 2
Description: Metallothionein 1 and 2

MTF1
Description: Metal regulatory transcription factor 1

MTO1
Description: Protein MTO1 homolog, mitochondrial

Curator: Bruce May
mTOR
Description: Serine/threonine-protein kinase mTOR

MUCIN
Description: Mucin-1

Curator: Bruce May
MYBBP1
Description: Myb-binding protein 1

Curator: Bruce May
MYC
MYC
Description: Myc proto-oncogene protein

Curator: Steve Jupe
MYD88
Description: Myeloid differentiation primary response protein MyD88

Curator: Steve Jupe
MYLK
Description: Myosin light chain kinase, smooth muscle

Curator: Steve Jupe
MYO1C
Description: Unconventional myosin-Ic

Curator: Bruce May
Myoglobin
Description: Myoglobin is an iron- and oxygen-binding protein

Curator: Steve Jupe
N-Ras
Description: GTPase NRas

Curator: Steve Jupe
N-WASP
Description: Neural Wiskott-Aldrich syndrome protein

Curator: Steve Jupe
NAE1
Description: NEDD8-activating enzyme E1 regulatory subunit

Curator: Bruce May
NANOG
Description: Homeobox protein NANOG

Curator: Bruce May
NAT10
Description: RNA cytidine acetyltransferase

Curator: Bruce May
NBD
NBD
Description: Nucleotide-binding domain

Curator: Steve Jupe
NCAM cis
Description: Neural cell adhesion molecules in cis-binding

Curator: Steve Jupe
NCAM trans
Description: Neural cell adhesion molecules in trans-binding

Curator: Steve Jupe
NCK1
Description: Cytoplasmic protein NCK1

Curator: Steve Jupe
NEDD8
Description: Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis

Curator: Bruce May
NEUROD1
Description: Neurogenic differentiation factor 1

Curator: Bruce May
NEUROG3
Description: Neurogenin-3

Curator: Bruce May
NFkappaB
Description: Nuclear factor NF-kappa-B

Curator: Steve Jupe
NGEF
Description: Ephexin-1

Curator: Steve Jupe
NGF
NGF
Description: Beta-nerve growth factor

NKX2-2
Description: Homeobox protein Nkx-2.2

Curator: Bruce May
NKX6-1
Description: Homeobox protein Nkx-6.1

Curator: Bruce May
NLGN
Description: Neuroligins

Curator: Steve Jupe
NODAL
Description: Nodal homolog

Curator: Bruce May
NOP2
Description: Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase

Curator: Bruce May
NoRC
Description: NoRC associated RNA is a non-coding RNA element which regulates ribosomal RNA transcription by interacting with TIP5, part of the NoRC chromatin remodeling complex

Curator: Bruce May
NOTCH1
Description: Neurogenic locus notch homolog protein 1

NOTCH2
Description: Neurogenic locus notch homolog protein 2

NOTCH3
Description: Neurogenic locus notch homolog protein 3

NOTCH4
Description: Neurogenic locus notch homolog protein 4

NPHS1
Description: Nephrins seems to play a role in the development or function of the kidney glomerular filtration barrier

Curator: Steve Jupe
NRP1
Description: Neuropilin-1

Curator: Steve Jupe
NRXN
Description: Neurexins

Curator: Steve Jupe
NSMAF
Description: Protein FAN

NSUN2
Description: tRNA (cytosine(34)-C(5))-methyltransferase

Curator: Bruce May
NSUN5
Description: Probable 28S rRNA (cytosine-C(5))-methyltransferase

Curator: Bruce May
NSUN6
Description: Putative methyltransferase NSUN6

Curator: Bruce May
NTN1
Description: Netrin-1

Curator: Steve Jupe
NuRD
Description: The NuRD complex contains seven subunits: the histone deacetylase core proteins HDAC1 and HDAC2, the histone-binding proteins RbAp46 and RbAp48, the metastasis-associated proteins MTA1 (or MTA2 / MTA3), the methyl-CpG-binding domain protein MBD3 (or MBD2) and the chromodomain-helicase-DNA-binding protein CHD3 or CHD4

Curator: Bruce May
OCT4
Description: Octamer-binding transcription factor 4 also known as Aggeliki (POU domain, class 5, transcription factor 1) is a protein that in humans is encoded by the POU5F1 gene

Curator: Bruce May
Oncogenic RAS
Description: The 3 Ras genes in humans (HRas, KRas, and NRas) are the most common oncogenes in human cancer

ONECUT1
Description: Hepatocyte nuclear factor 6

Curator: Bruce May
ORC
ORC
Description: Origin recognition complex

Curator: Lisa Matthews
ORC1
Description: Origin recognition complex subunit 1

Curator: Lisa Matthews
ORC2-6
Description: Origin recognition complex subunits 2 to 6

Curator: Lisa Matthews
OST
OST
Description: Oligosaccharyltransferase

Curator: Bruce May
p14ARF
Description: Tumor suppressor ARF

P16INK4A
Description: p16Ink4a is a protein involved in regulation of the cell cycle. Currently, p16Ink4a is considered a tumor suppressor protein

P23
P23
Description: Prostaglandin E synthase 3

PABP
Description: Polyadenylate-binding protein

Curator: Bruce May
PAI1
Description: Plasminogen activator inhibitor 1

Curator: Steve Jupe
PAK1
Description: Serine/threonine-protein kinase PAK 1

Curator: Steve Jupe
PAKs
Description: Family of serine/threonine-protein kinase

Curator: Steve Jupe
PARP1,2
Description: Poly [ADP-ribose] polymerase 1 and 2

PAX4
Description: Paired box protein Pax-4

Curator: Bruce May
PAX6
Description: Paired box protein Pax-6

Curator: Bruce May
PCNA
Description: Proliferating cell nuclear antigen

PCSK1
Description: Neuroendocrine convertase 1

Curator: Bruce May
PCSK2
Description: Neuroendocrine convertase 2

Curator: Bruce May
PDE6
Description: Set of Rod cGMP-specific 3',5'-cyclic phosphodiesterases

PDX1
Description: Pancreas/duodenum homeobox protein 1

Curator: Bruce May
PEBP1
Description: Phosphatidylethanolamine-binding protein 1

Curator: Steve Jupe
PEPSINS
Description: A pepsin is an enzyme that breaks down proteins into smaller peptides

Curator: Bijay Jassal
PERK
Description: Eukaryotic translation initiation factor 2-alpha kinase 3, dimer

Curator: Bruce May
Peroxisomal matrix protein
Description: Peroxisomes import folded, even oligomeric, proteins, which distinguishes the peroxisomal translocation machinery from the well-characterized translocons of other organelles.

Curator: Bruce May
PEX3
Description: Peroxisomal biogenesis factor 3

Curator: Bruce May
PEX5
Description: Peroxisomal targeting signal 1 receptor

Curator: Bruce May
PEX19
Description: Peroxisomal biogenesis factor 19

Curator: Bruce May
PI3K
Description: Phosphoinositide 3-kinase

Curator: Steve Jupe
PI3KG
Description: Generic representation of a G-protein-coupled receptor

Curator: Steve Jupe
PKA
PKA
Description: cAMP-dependent protein kinase catalytic subunit alpha

Curator: Bruce May
PKC
PKC
Description: Protein kinase C

Curator: Steve Jupe
PKNs
Description: Set of Serine/threonine-protein kinases

PLASMIN
Description: Plasmin

Curator: Steve Jupe
PLASMINOGEN
Description: Plasminogen

Curator: Steve Jupe
PLAUR
Description: Urokinase plasminogen activator surface receptor

Curator: Bruce May
PLC
PLC
Description: Phospholipase C (Set)

Curator: Steve Jupe
PLCbeta1
Description: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

Curator: Steve Jupe
PLCepsilon1
Description: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

Curator: Steve Jupe
PLCgamma1
Description: 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Curator: Steve Jupe
PLXNB1
Description: Plexin-B1

Curator: Steve Jupe
podocin
Description: Podocin is a protein component of the filtration slits of podocytes. Glomerular capillary endothelial cells, the glomerular basement membrane and the filtration slits function as the filtration barrier of the kidney glomerulus

Curator: Steve Jupe
POFUT1
Description: GDP-fucose protein O-fucosyltransferase 1

POGLUT1
Description: Protein O-glucosyltransferase 1

POLA
Description: DNA polymerase alpha

Curator: Lisa Matthews
POLB
Description: DNA polymerase beta

POLD,E
Description: DNA polymerase delta and epsilon

POLRMT
Description: DNA-directed RNA polymerase, mitochondrial

Curator: Bruce May
PORCN
Description: Protein-serine O-palmitoleoyltransferase porcupine