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Receptors (111 components)

ACVR
Description: Family of Activin receptors

ADAM22
Description: Disintegrin and metalloproteinase domain-containing protein 22

Curator: Bruce May
ADAM23
Description: Disintegrin and metalloproteinase domain-containing protein 23

Curator: Bruce May
ADRA2A-C
Description: Alpha-2A adrenergic receptor

Curator: Steve Jupe
AGER
Description: Receptor for advanced glycation endproducts

Curator: Steve Jupe
AVPR2
Description: Vasopressin V2 receptor

Curator: Bruce May
BCR
BCR
Description: The B-cell receptor is a transmembrane receptor protein located on the outer surface of B cells

Curator: Steve Jupe
BMPR
Description: Family of Bone morphogenetic protein receptor

BOC
BOC
Description: Brother of CDO

Curator: Bruce May
Cadherins
Description: Calcium-dependent adhesion proteins are a class of type-1 transmembrane proteins

Curator: Bruce May
CD3
CD3
Description: Cluster of differentiation 3 protein complex containing CD3 gamma-chain, CD3 delta-chain, CD3 epsilon-chain and two CD3 zeta-chain

Curator: Steve Jupe
CD28
Description: T-cell-specific surface glycoprotein CD28

Curator: Steve Jupe
CD40-CD40L
Description: CD40 ligand is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 on antigen-presenting cells

Curator: Steve Jupe
CD40
Description: Tumor necrosis factor receptor superfamily member 5

Curator: Steve Jupe
CD40L
Description: CD40 ligand

Curator: Steve Jupe
CD80-CD28
Description: Cluster of Differentiation 28 is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. B7 is a type of peripheral membrane protein found on activated antigen presenting cells

Curator: Steve Jupe
CD80
Description: T-lymphocyte activation antigen CD80

Curator: Steve Jupe
CDON
Description: Cell adhesion molecule-related/down-regulated by oncogenes

Curator: Bruce May
CLR
CLR
Description: C-type lectin receptors comprise a large family of receptors that bind to carbohydrates in a calcium-dependent manner. The lectin activity of these receptors is mediated by conserved carbohydrate-recognition domains

Curator: Steve Jupe
CRIPTO
Description: Cripto is an EGF-CFC or epidermal growth factor-CFC, which is encoded by the Cryptic family 1 gene

Curator: Bruce May
Cytokine receptor
Description: Cytokine receptors are receptors that bind cytokines

Curator: Steve Jupe
DAP12
Description: DAP12 signaling subunits are highly conserved in evolution and associate with a large family of receptors in hematopoietic cells, including dendritic cells, plasmacytoid dendritic cells, neutrophils, basophils, eosinophils, mast cells, monocytes, macrophages, natural killer cells, and some B and T cells

Curator: Steve Jupe
DCC
DCC
Description: Deleted in Colorectal Carcinoma is a protein which in humans is encoded by the DCC gene

Curator: Steve Jupe
EGFR
Description: Epidermal growth factor receptor

EPHA
Description: Ephrin type A receptor family

Curator: Steve Jupe
EPHB
Description: Ephrin type B receptor family

Curator: Steve Jupe
ERBB2
Description: Receptor tyrosine-protein kinase erbB-2

ERBB4
Description: Receptor tyrosine-protein kinase erbB-4

FAS
FAS
Description: Tumor necrosis factor receptor superfamily member 6

FCER1
Description: FCER1 is the high-affinity receptor for the Fc region of immunoglobulin E

Curator: Steve Jupe
FCGR
Description: FCgammaR belong to the immunoglobulin superfamily

Curator: Steve Jupe
FGFR1
Description: Fibroblast growth factor receptor 1

FGFR2
Description: Fibroblast growth factor receptor 2

FGFR3
Description: Fibroblast growth factor receptor 3

FGFR4
Description: Fibroblast growth factor receptor 4

FZD
FZD
Description: Representation for Frizzled famlily, a receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin (CTNNB1) canonical signaling pathway

GFR
GFR
Description: GDNF family receptor

Curator: Steve Jupe
GPCR CLASS A 1
Description: Rhodopsin-like receptors are a family of proteins that comprise the largest group of G protein-coupled receptors. The currently known superfamily members include the rhodopsin-like GPCRs (this family), the secretin-like GPCRs, the cAMP receptors, the fungal mating pheromone receptors, and the metabotropic glutamate receptor family

Curator: Steve Jupe
GPCR CLASS B 2
Description: The secretin-receptor family GPCRs include vasoactive intestinal peptide receptors and receptors for secretin, calcitonin and parathyroid hormone/parathyroid hormone-related peptides

Curator: Steve Jupe
GPCR CLASS C 3
Description: The class C G-protein-coupled receptors are a class of GPCRs that include the metabotropic glutamate receptors and several additional receptors

Curator: Steve Jupe
GPCR generic
Description: Generic representation of a G-protein-coupled receptor

Curator: Steve Jupe
GPIb-IX-V
Description: Glycoprotein Ib-IX-V Receptor Complex

Curator: Steve Jupe
GPR161
Description: G-protein coupled receptor 161

GPVI
Description: Platelet glycoprotein VI

Curator: Steve Jupe
Growth Hormone receptor
Description: Growth hormone receptor is a protein that in humans is encoded by the GHR gene

Curator: Steve Jupe
ICAM3
Description: Intercellular adhesion molecule 3 is a protein that in humans is encoded by the ICAM3 gene

Curator: Steve Jupe
IGF1R
Description: Insulin-like growth factor 1 receptor

IL1BR
Description: Interleukin 1B receptor

Curator: Steve Jupe
IL1RAP
Description: Interleukin-1 receptor accessory protein

Curator: Steve Jupe
IL1RAPL1
Description: Interleukin-1 receptor accessory protein-like 1

Curator: Steve Jupe
IL2R
Description: Interleukin 2 receptor

Curator: Steve Jupe
IL3R
Description: Interleukin 3 receptor

Curator: Steve Jupe
IL4R
Description: Interleukin 4 receptor

Curator: Steve Jupe
IL6R
Description: Interleukin 6 receptor

Curator: Steve Jupe
IL7R
Description: Interleukin 7 receptor

Curator: Steve Jupe
IL10R
Description: Interleukin 10 receptor

Curator: Steve Jupe
IL12R
Description: Interleukin 12 receptor

Curator: Steve Jupe
IL13R
Description: Interleukin 13 receptor

Curator: Steve Jupe
IL17R
Description: Interleukin 17 receptor

Curator: Steve Jupe
IL20R
Description: Interleukin 20 receptor

Curator: Steve Jupe
ILR Unknown
Description: Representation of an unknown interleukin receptor

Curator: Steve Jupe
INSR
Description: Insulin receptor

Integrins active
Description: Integrins

Curator: Steve Jupe
Integrins resting
Description: Integrins resting

Curator: Steve Jupe
JAM3
Description: Junctional adhesion molecule C is a protein that in humans is encoded by the JAM3 gene

Curator: Steve Jupe
LEPR
Description: Key player in the regulation of energy balance and body weight control

LGI-1
Description: Leucine-rich glioma-inactivated protein 1

Curator: Bruce May
LRP
LRP
Description: Prolow-density lipoprotein receptor-related protein 1

MBL
MBL
Description: Mannose-binding lectin is a lectin that is instrumental in innate immunity

Curator: Steve Jupe
MET
MET
Description: Hepatocyte growth factor receptor

MHC I
Description: MHC class I molecules are one of two primary classes of major histocompatibility complex (MHC) molecules (the other being MHC class II) and are found on the cell surface of all nucleated cells in the bodies of jawed vertebrates

Curator: Steve Jupe
MHC II
Description: MHC class II molecules are a class of major histocompatibility complex (MHC) molecules normally found only on antigen-presenting cells such as dendritic cells, mononuclear phagocytes, some endothelial cells, thymic epithelial cells, and B cells

Curator: Steve Jupe
MST1R
Description: Macrophage-stimulating protein receptor

NGFR
Description: Tumor necrosis factor receptor superfamily member 16

NRP1 PLXNA2
Description: Neuropilin-1 and Plexin-A family

Curator: Steve Jupe
NTRK3
Description: NT-3 growth factor receptor

Curator: Steve Jupe
Nuclear receptors
Description: Nuclear receptors are a class of proteins found within cells that are responsible for sensing steroid and thyroid hormones and certain other molecules

P-selectin
Description: P-selectin is a protein that in humans is encoded by the SELP gene

Curator: Steve Jupe
P2RY1
Description: P2Y purinoceptor 1

Curator: Steve Jupe
P2RY12
Description: P2Y purinoceptor 12

Curator: Steve Jupe
PAR1,3,4
Description: Proteinase-activated receptor 1, 3 and 4

Curator: Steve Jupe
PDGFR
Description: Generic platelet-derived growth factor receptor

PLXNA2
Description: Plexin-A1

Curator: Steve Jupe
Prolactin receptor
Description: The prolactin receptor interacts with prolactin as a transmembrane receptor

Curator: Steve Jupe
PTPRD
Description: Receptor-type tyrosine-protein phosphatase delta

Curator: Steve Jupe
PTPRS
Description: Receptor-type tyrosine-protein phosphatase S

Curator: Steve Jupe
Receptor generic
Description: Representation of a generic receptor

Curator: Steve Jupe
RET
RET
Description: Proto-oncogene tyrosine-protein kinase receptor Ret

Curator: Steve Jupe
ROR2 RYK
Description: Representation of Tyrosine-protein kinase transmembrane receptor ROR2 and/or Tyrosine-protein kinase RYK

Scavenger receptor class A
Description: Scavenger receptors type 1 (SR-A1) and 2 (SR-A2) are trimers that preferentially bind modified LDL, either acylated (acLDL) or oxidized (oxLDL). They have a collagen-like domain, which is essential for ligand binding

Curator: Steve Jupe
Scavenger receptor class B
Description: Scavenger receptor class B member 1 (SRB1) also known as SR-BI is a protein that in humans is encoded by the SCARB1 gene.[3] SR-BI functions as a receptor for high-density lipoprotein

Curator: Steve Jupe
Scavenger receptor class D
Description: Scavenger receptors are a group of receptors that recognize modified low-density lipoprotein

Curator: Steve Jupe
Scavenger receptor class E
Description: Scavenger receptors are a group of receptors that recognize modified low-density lipoprotein

Curator: Steve Jupe
Scavenger receptor class G
Description: Scavenger receptors are a group of receptors that recognize modified low-density lipoprotein

Curator: Steve Jupe
SCF KIT
Description: Mast/stem cell growth factor receptor Kit

SHR
SHR
Description: Steroid hormone receptors are generally intracellular receptors (typically cytoplasmic or nuclear) and initiate signal transduction for steroid hormones which lead to changes in gene expression over a time period of hours to days

SRP receptor
Description: Signal recognition particle receptor is a dimer composed of 2 different subunits that are associated exclusively with the rough ER in mammalian cells

Curator: Bruce May
TBXA2R
Description: Thromboxane A2 receptor

Curator: Steve Jupe
TCR-CD3
Description: Representation of TCR and CD3

Curator: Steve Jupe
TCR-MHC I
Description: The T-cell receptor is a molecule found on the surface of T cells that is responsible for recognizing fragments of antigen as peptides bound to MHC class I in this case (major histocompatibility complex) molecules

Curator: Steve Jupe
TCR-MHC II
Description: The T-cell receptor is a molecule found on the surface of T cells that is responsible for recognizing fragments of antigen as peptides bound to MHC class II in this case (major histocompatibility complex) molecules

Curator: Steve Jupe
TCR
TCR
Description: Pre T-cell antigen receptor alpha and beta

Curator: Steve Jupe
TGFBR
Description: Set of TGF-beta receptor

TLR
TLR
Description: Toll-like receptors are single, membrane-spanning, non-catalytic receptors

Curator: Steve Jupe
TNFR
Description: Tumor necrosis factor receptor superfamily member 1A

TNFRSF10
Description: Tumor necrosis factor receptor superfamily member 10

Curator: Steve Jupe
TNFSF9-TNFRSF9
Description: TNFSF9 is a type 2 transmembrane glycoprotein belonging to the TNF superfamily, expressed on activated T Lymphocytes. And tumor necrosis factor receptor superfamily member 9

Curator: Steve Jupe
TREM2
Description: Triggering receptor expressed on myeloid cells 2 is a protein that in humans is encoded by the TREM2 gene

Curator: Steve Jupe
UNC5
Description: UNC-5 is a receptor for netrins and uses repulsion to direct axons while the other netrin receptor UNC-40 attracts axons to the source of netrin production

Curator: Steve Jupe
VEGFR
Description: Generic vascular endothelial growth factor receptor

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